Potential diabetes drug target identified

TORONTO (UPI) -- Canadian scientists announced the discovery of a novel signaling pathway to the gut, brain and liver that lowers blood sugar when it is activated.

The scientists at the Toronto General Hospital Research Institute, led by Dr. Tony Lam, used a rat model to discover that fats can activate a subset of nerves in the intestine, which then send a signal to the brain and subsequently to the liver to lower glucose production.

"This is a new approach in developing more effective methods to lower glucose or blood sugar levels in those who are obese or have diabetes," said Lam.

"We already knew that the brain and liver can regulate blood glucose levels," he said, "but the question has been, how do you therapeutically target either of these two organs without incurring side effects? We may have found a way around this problem by suggesting that the gut can be the initial target instead.

"If new medicines can be developed that stimulate this sensing mechanism in the gut, we may have an effective way of slowing down the body's production of sugar, thereby lowering blood sugar levels in diabetes," said Lam.

The research appears in the online issue of the journal Science in advance of print publication.

Copyright 2008 by United Press International
www.arcamx.com

Study points to possible malaria vaccine

DALLAS (UPI) -- U.S. and British scientists said they might have discovered why some species can nearly never interbreed -- a key insight into the basis of reproduction.

University of Texas Southwestern Medical Center researchers said their finding might point to a possible malaria vaccine, thwarting the disease that kills about 1 million people each year, primarily children in sub-Saharan Africa.

The researchers found sexual reproduction begins with two genetically different steps: First, two reproductive cells must latch onto each other with one protein, and secondly they must fuse their membranes to form a single cell using a different protein.

The scientists collaborated with malaria experts at Imperial College London and found the parasite causing malaria also uses that two-step process. When they blocked "male" and "female" malarial cells from fusing, spread of the mosquito-borne disease was stopped.

The research is to appear in the April 14 issue of the journal Genes and Development and is now available at the journal's Web site.

source: www.arcamax.com
Copyright 2008 by United Press International

PT Appointment

I had a Physical Therapy appointment today. I just like my P'Therapist because she made a very good massage. I got before back pains but since I was having massage and fango, I am feeling very better now. My back pains don't keep on coming back just like before. Oh yeah..guess this is what I got working so hard here in Europe..So now I just stayed at home doing blogging and meeting friends online..hehehe!!

I was before in different PT's but I was not contented and satisfied the way they made the massage. Finally I found the right clinic or Reha as called in German and I am very satisfied with their service.

As I was today in my appointment, it was snowing very hard. I even got some photos which I took as I was in the second floor of the clinic. Hopefully will post it tomorrow once I download it.

Got to sign-off now as I was also not feeling so good having some headache...guess migraine too!! Hope to visit fellow friends bloggers tomorrow when I have time as I also have a lot of errands to do even got another appointment for my gycologist.

Finally thanks guys for keep on visiting me here...will visit you once I got time..Thanks a lot!!!

Wish everyone a nice day in US and evening in Europe!!!God bless us all!!

Reasons for sleeping and waking up early

Evening at 9 - 11pm: is the time for eliminating unnecessary/toxic chemicals (detoxification) from the body's system (lymph nodes). This time should be spent by relaxing or listening to music. If during this time a housewife is still in an unrelaxed state such as washing the dishes or monitoring children doing their homework, this will have a negative impact on health.

Evening at 11pm - 1am: is the detoxification process in the liver, and ideally should be done in a deep sleep state.
Early morning 1 - 3am: detoxification process in the gall, also ideally done in a deep sleep state.

Early morning 3 - 5am: detoxification in the lungs. Therefore there will sometimes be a severe cough for cough sufferers during this time. Since the detoxification process had reached the respiratory tract, there is no need to take cough medicine so as not to interfere with toxin removal process.

Morning 5 - 7am: detoxification in the colon, you should empty your bowel (usually after waking up- walk around a bit to shake "it" down). Some advice drinking a glass of clean water right after waking up.

Morning 7 - 9am: absorption of nutrients in the small intestine, you should be having breakfast at this time. Breakfast should be earlier, before 6:30am, for those who are sick. Breakfast before 7:30am is very beneficial to those wanting to stay fit. Those who always skip breakfast, they should change their habits, and it is still better to eat breakfast late until 9 - 10am rather than no meal at all.

Sleeping so late and waking up too late will disrupt the process of removing unnecessary chemicals. Aside from that, midnight to 4:00 am is the time when the bone marrow produces blood. Therefore, have a good sleep and don't sleep late.

TAKE CARE OF YOUR HEALTH, IT'S THE BEST INVESTMENT YOU'LL EVER MAKE-- FOR FREE!

What a Crazy Day!!

I suppose to have an appointment at my Physical Therapist for massage today. As I woke up around 8am, I felt my head very heavy, so I decided to call them to cancel my appointment. It was raining so hard this morning, a little stormy and really a bad weather.

In short it is a crazy weather today because right now, the sun is shining again. I just went out a while ago picking up the newspaper and some mails outside and the rain starting pouring again. I believed sometimes the cause of my headache and migraine is this crazy weather we have in Germany. What you do think???

So I just spent my day, staying in the house, do some cooking and blog hopping again!!..I guess the pop-ups are all gone now!!! i hope so as I never encountered it during my blog hopping!!! So please dear hackers, I hope you see the hard work we put on our blogs everyday!!! just some respect and do honest work and you will also be rewarded!!!

God bless us all!!!

The top five cancer-causing foods!!

TAKE CARE OF YOUR HEALTH, IT'S THE BEST INVESTMENT YOU'LL EVER MAKE-- FOR FREE!

The top five cancer-causing foods are:

1. Hot dogs
Because they are high in nitrates, the Cancer Prevention Coalition advises that children eat no more than 12 hot dogs a month. If you can't live without hot dogs, buy those made without sodium nitrate.

2. Processed meats and bacon
Also high in the same sodium nitrates found in hot dogs, bacon, and other processed meats raise the risk of heart disease. The saturated fat in bacon also contributes to cancer.

3. Doughnuts
Doughnuts are cancer-causing double trouble. First, they are made with white flour, sugar, and hydrogenated oils, then fried at high temperatures. Doughnuts, says Adams , may be the worst food you can possibly eat to raise your risk of cancer.

4. French fries
Like doughnuts, French fries are made with hydrogenated oils and then fried at high temperatures. They also contain cancer- causing acryl amides which occur during the frying process. They should be called cancer fries, not French fries,
said Adams .

5. Chips, crackers, and cookies
All are usually made with white flour and sugar. Even the ones whose labels claim to be free of trans-fats generally contain small amounts of trans-fats.

I am Stress too!!

I guess, I am also stress for the past days until now. Since I got pop-ups last Saturday, I can't no longer sleep good thinking that I lost my blogs the next day I woke up. I tried my best to resolved it and finally yesterday, they are all gone with the help of some blogger friends.

I just felt so tired today, my back ache, my head just ache and my whole body aches... It is just perfect timing that my friend forwarded me an article on how to reduce stress which I also posted here to share it with you. I felt quite relieved but still feel very very tired until now.

So my dear bloggers friends and all friends here , I might not visit you often this week until these pop-ups will be gone. I wrote here yesterday some tips on how to resolve it.. So I am also recommending it to you. I hope it will help a bit as that's what I also did and it worked. hopefully for you too!!
See you all as soon as I can!!..

Dear readers and visitors, thanks a lot for taking your time to visit me here. I really appreciate it!!!

Tschuss!!!

BRAIN DAMAGING HABITS

My friend sent me this helpful tips for our health..hope you got some insights from this too!!
Enjoy your coming weekend!!!

1. No Breakfast
People who do not take breakfast have a lower blood sugar level.
This leads to an insufficient supply of nutrients to the brain causing brain degeneration.

2. Overeating
It causes hardening of the brain
arteries, leading to a decrease in mental power.

3. Smoking
It causes multiple brain shrinkage and may lead to Alzheimer disease.

4. High Sugar consumption
Too much sugar will interrupt the absorption of proteins and nutrients causing malnutrition and may interfere with brain development.

5. Air Pollution
The brain is the largest oxygen consumer in our body. Inhaling polluted air decreases the supply of oxygen to the brain, bringing about a decrease in brain efficiency.

6. Sleep Deprivation
Sleep allows our brain to rest. Long term deprivation from sleep will accelerate the death of brain cells.

7. Head covered while sleeping
Sleeping with the head covered increases the concentration of carbon dioxide and decrease intake of oxygen.

8. Working your brain during illness
Working hard or studying with sickness may lead to a decrease in effectiveness of the brain.

9.Lacking in stimulating thoughts
Thinking is the best way to train our brain, lacking in brain stimulation thoughts may cause brain shrinkage.

10. Talking Rarely
Intellectual conversations will promote the efficiency of the brain

What A Crazy Weather!!

Did I mentioned yesterday about the storm in Germany for the past days..right?? and I also said that I will wait what's going on for the rest of the day?? well, yesterday we had again a crazy weather. In the morning sunshine was there. As I went shopping in Burglengenfeld in the afternoon, I was caught by snow. Then comes the rain later. What a crazy weather. We even have 3 seasons in a day sometimes; sunny, rainy and snow time..

Just an honest advice to everybody who want to come to Germany especially in the state of Bavaria, just don't trust the weather. Always bring with you umbrellas and rain coats and even sweaters when the weather sometimes becomes cold esp. in the night.

And what I got now from yesterday's crazy weather??? got some colds and a bit headache. The weather forecast also said that some parts of Germany will be snowing this week. Even the weather last night went down to -7 degree centigrade..really freezing cold!!

Today comes the sunshine again..hope the weather will be the same the rest of the day so I can go a bit walking if I am feeling better..

have a nice day to all of you!!! thanks for always visiting me here!!!

clearer view of the castle in Burglengenfeld..

view from afar..Burglengenfeld castle..very dark sky..It was already raining
as I took this photo.

where I parked my car during grocery shopping..at this time it was already snowing..sorry just don't have a good camera to catch the dropping of snow.

Doctor's Appointment!!

I almost forgot to call about my husband doctor's appointment tomorrow..it's good that I remember it before I go to shopping today!! My husband had a bike accident last year and broke his ankle and had operation. Until now he is still having some therapy. He always complains for the pain in his foot but he have to go to work!! such a pity for my Mann!!

The receptionist in the PT clinic is a very nice lady.. I also did not know that she already reserved for me an appointment for a Massage therapy!! I'm happy to know about it!! I just need a manual therapy for my aching back and shoulders!!

thanks to this very accommodating receptionist!!